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The Global Health Network congratulates the Zuckerbergs on this game-changing initiative. Our global health research community believes that only through gathering evidence to characterize, understand and prove what intervention work, can there be true reduction in early mortality from disease. We also know what impedes this research and that is what we are working to address through sharing knowledge, methods and technology. It would be very interesting to discuss this with the Chan Zuckerberg initiative and see whether our approaches and methods can help speed up your progress. Please see this Sky News interview where we were asked by Sky News to comment on the announcement about this bold vision to tackle all diseases.