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To address the broad scope and reach of genomics in society, applications are invited from investigators representing a wide range of disciplines, including but not limited to the social, behavioral and communication sciences, ethics, philosophy, history, economics, and epidemiology as well as the basic, clinical and computational sciences. Applications may propose well-integrated single or multi-disciplinary studies using either single or mixed methods. Proposed methods may include data-generating qualitative and quantitative approaches, legal, economic and normative analyses, or other analytical or conceptual research methodologies. Applications to this FOA should propose exploratory or developmental studies that can be accomplished in two years. Often these applications will generate pilot data in preparation for a larger study.
Areas of Research Interest
The specific areas of research interest targeted through this FOA derive from the most recent Strategic Plan for the future of human genome research, as described in "Charting a Course for Genomic Medicine from Base Pairs to Bedside,"(Nature, 470, 2011). That Strategic Plan outlines the following four broad categories of research on high priority issues that arise at the interface of genomics and society.
Genomic Research. Projects in this area may examine and address the issues that arise in the design and conduct of genomic research, particularly research that involves the production, analysis and broad sharing of individual genomic data that is frequently coupled with detailed health information.
Genomic Health Care. Projects in this area may explore how rapid advances in genomic technologies and the availability of increasing amounts of genomic information influence how health care is provided and how it affects the health of individuals, families and communities.
Broader Societal Issues. Projects in this area may examine the normative underpinnings of beliefs, practices and policies regarding genomic information and technologies, as well as the implications of genomics for how such issues as health, disease, and individual responsibility are conceptualized and understood.
Legal, Regulatory and Public Policy Issues. Projects in this area may explore the effects of existing genomic research, health and public policies and regulations and provide data to inform the development of new policies and regulatory approaches.
- The Fogarty International Center is interested in supporting research on ethical issues related to human genome research relevant to low and middle income countries, in particular, studies conducted by investigators in these countries through the Small Research Grant Program (R03) (PA-14-277) http://grants.nih.gov/grants/guide/pa-files/PA-14-277.html.
- Foreign institutions can also apply to the companion Regular Research Program (R01) (PA-14-276) http://grants.nih.gov/grants/guide/pa-files/PA-14-276.html and Exploratory/Developmental Research Program (R21) (PA-14-278) http://grants.nih.gov/grants/guide/pa-files/PA-14-278.html.
For larger multi-disciplinary studies that are building on preliminary data and require funding beyond two years, applicants may wish to consider the ELSI Regular Research Grant (R01) FOA, which provides funding for up to five years.
For projects that are primarily exploratory in nature, or designed to generate pilot data in preparation for a larger study, applicants should consider the ELSI R21 FOA, which provides a total of up to $275,000 in direct costs over two years.
For small single-investigator projects, applicants may wish to consider the ELSI R03 FOA, which provides a total of up to $50,000 in direct costs a year for two years.